I don't really think so. I know she got locked up for life. But if she was maybe the same age as Eda's mother. Then the four-year time skip isn't long enough for her to have passed on from old age.

If she was in her sixties or possibly seventies when we first saw her. Then I think she's still around but just locked up in prison for life. It would take maybe ten or twenty years after the events of the last episode for her to have passed on from old age.

But that's only if she was in her sixties or seventies around the time the show first started.